Single-cell alternative splicing analysis with Expendition reveals splicing dynamics during neuron differentiation. Song et al

Published: 9 January 2019| Version 1 | DOI: 10.17632/vhtn65y828.1
Contributor:
Yan Song

Description

smRNA-FISH demonstrate presence of constitutive exons or alternative splicing exons in two different cell-types: iPSCs and MNs. For PKM, exon 10 is primary included in iPSCs, but not observed in MNs, whereas exon 9 is primarily observed in MNs but not in iPSCs. For MAP4K4, alternative exon 16 is less included in iPSCs, but more included in MNs.

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Institutions

University of California San Diego

Categories

Laser Microscopy

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