Supplementary Materials- A prospective cohort study examining the association of claw anatomy and sole temperature with the development of claw horn disruption lesions in dairy cattle
Description
Supplementary Table S1. Case definitions and descriptions of the grading system for sole haemorrhage, sole ulcers and white line lesions. Supplementary Table S2. Descriptive Statistics of explanatory variables at each time point. Continuous variables are presented alongside the mean, standard deviation (SD), range and number of missing values (%). Categorical variables are presented alongside the frequency within each level (%). T1-Precalving, n = 1982, T2- Calving, n = 2082. Farm and Parity variables are presented at the T1-Precalving timepoint . Supplementary Table S3. Results from univariable analysis with logistic regression of T1-Precalving and T2-Calving explanatory variables with white line lesion at T3-Early as an outcome. Odds ratios are calculated, either for a single unit increase or compared to the reference level. Supplementary Table S4. Results from univariable analysis with logistic regression of T1-Precalving and T2-Calving explanatory variables with sole lesion at T3-Early as an outcome. Odds ratios are calculated, either for a single unit increase or compared to the reference level. Supplementary Table S5. Pairwise Pearson’s Correlation Coefficients (r) between explanatory variables are presented. Supplementary Table S6. The model-adjusted probabilities of sole and white line lesions at each timepoint from four multivariable fixed-effect logistic regression models (1a, 1b, 2a and 2b). The arithmetic mean of the variable (sole horn thickness or foot angle) was calculated after grouping by industry recommended levels. Supplementary Figure S1. Schematic showing the study design and variables recorded at each timepoint. Timepoints are described as days relative to the expected calving date. Supplementary Figure S2. Data handling workflow to create the final datasets used in the analysis.