Systematic Elucidation and Pharmacological Targeting of Tumor-Infiltrating Regulatory T Cell Master Regulators
Published: 11 April 2023| Version 1 | DOI: 10.17632/vnrsbb4gk9.1
Christopher M. Jackson,
Angelo De Marzo,
Charles G. Drake,
Data accompanying the manuscript "Systematic Elucidation and Pharmacological Targeting of Tumor-Infiltrating Regulatory T Cell Master Regulators"-- includes RNA-Seq of sorted T-cell populations from patients across four tumor types, inferred T-cell ARACNe network, sgRNA counts matrices for pooled CRISPRko screen, PLATE-Seq of drug perturbational experiment, and single-cell RNA-Sequencing of spleen and tumor from gemcitabine-treated versus control mouse Tregs, as well code files used for data analysis.
RNA Sequencing, Immunotherapy, Drug Screening, Human T Regulatory Cell, Single-Cell RNA Sequencing