The prenatal application of functionalized collagen scaffolds in a fetal sheep wound model leads to subtle and essential changes in gene expression levels that culminate in enhanced postnatal skin regeneration (2024)
Published: 22 November 2024| Version 2 | DOI: 10.17632/vsbfvc342x.2
Contributors:
Merel Gansevoort, Corien Oostendorp, Linde Bouwman, Dorien Tiemessen, Paul Geutjes, Wout Feitz, Toin van Kuppevelt, Willeke DaamenDescription
Supplemental datasets belonging to original research article (DOI: 10.1007/s13770-024-00667-9). Data are presented as expression fold changes obtained from microarrays (Ovine Gene 1.0 ST Arrays, Affymetrix, Santa Clara, CA, USA)). Abbreviations: NL = normal skin UNTR = untreated full thickness skin defect COL = collagen scaffold COL-HEP/GF = collagen scaffold with heparin, fibroblast growth factor 2 and vascular endothelial growth factor.
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Steps to reproduce
For materials and methods we refer readers to the original research article to which these datasets belong. The article is available from the journal 'Tissue engineering and regenerative medicine' at DOI: 10.1007/s13770-024-00667-9.
Institutions
Radboudumc
Categories
cDNA Microarray, Differential Gene Expression