Suspicious Ultrasound Characteristics, IMC and Brafv600e mutation associated with central lymph node metastasis

Published: 25 August 2019| Version 2 | DOI: 10.17632/vywrrtywk4.2
, Lin-Xue Qian


From January 2016 to March 2018, we identified a cohort of patients with classic papillary thyroid carcinoma who underwent cervical US and were diagnosed by postoperative pathology. Fine-needle aspiration biopsies were analyzed for the presence of BRAFV600E, and immunohistochemistry was used to detect tumor markers. US imaging was performed in accordance with a standardized protocol. A model to determine the risk of central lymph node metastasis was established using the outcomes of univariate and multivariate analyses.



Capital Medical University Affiliated Beijing Friendship Hospital


Gene Mutation, Thyroid Cancer, Metastasis, Immunohistochemistry, Cervical Lymph Nodes