Evaluation of sugar content and erosive potential of commonly prescribed Orally Dispersible Tablets- An In vitro study
Description
Drug class: Pharmacological classification Generic name: Name of the drug Duration: Based on the usage; Short term or long term Trade name: Commercially available preparation name as marketed pH: acidic potential total sugar as per dose form of the tablet: It is total amount of sugar present in the tablet as dispensed. % sugar content: percentage sugar content per 100mg % Titratable acidity: acidic potential of the tablet
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We aimed to assess and compare the Total Sugar Content, pH, solubility, and Titratable Acidity of long-term and short-term Orally Dispersible Tablets (ODT) and different drug classes. Measurement of pH was done using digital pH meter. The titratable acidity was measured by titrating the samples with known amount of 0.1N sodium hydroxide and phenolphthalein indicator. Total sugars was estimated by phenol sulphuric acid method. Solubility was assessed by filtration method.