Effect of resistance training versus metformin intervention on non-obese patients with polycystic ovary syndrome

Published: 29 October 2024| Version 1 | DOI: 10.17632/w8rt2r7vx3.1
Contributor:
Yu Chen

Description

1. Research Hypothesis: Our research hypothesis is that resistance training, compared to standard metformin treatment, will lead to significant improvements in body composition, muscle strength, blood biochemistry, and menstrual symptoms in non-obese patients with polycystic ovary syndrome (PCOS). We expect that resistance training will not only effectively increase muscle mass and reduce body fat but also improve metabolic and endocrine abnormalities commonly associated with PCOS, such as hyperandrogenism and insulin resistance. 2. Data Collection Methods: We recruited non-obese PCOS patients who met specific inclusion criteria, with all participants randomly assigned to either a resistance training intervention group or a control group receiving standard metformin treatment. The study period spanned twelve weeks, during which we assessed participants at baseline and post-intervention across several measures. The collected data included: anthropometric measurements and body composition, muscle strength, blood biochemistry, menstrual symptoms. 3. Data Interpretation and Application: These findings suggest that resistance training not only aids in optimizing body composition in non-obese PCOS patients but also has beneficial effects on metabolic and endocrine functions. The improvements in insulin sensitivity and androgen levels may be due to resistance training’s role in enhancing muscle insulin sensitivity, reducing body fat, and regulating androgen secretion. Clinically, these results indicate that resistance training could serve as an effective intervention for PCOS patients, particularly those aiming to improve body composition and metabolic health.

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Categories

Endocrinology, Sports Medicine, Nutrition, Exercise Physiology, Metabolic Disorder, Health, Clinical Research, Health Promotion and Health Maintenance, Exercise Promotion, Biomedical Research

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