Supplementary data for genome-wide DNA methylation and gene expression analysis of human blood in patients with metabolic syndrome
Description
These supplementary data, associated with Baek et al.[1], comprise the raw data, and the analyzed and filtered epigenetic biomarker data, for patients with MetS and controls. Raw data (GEO accession: GSE181647) included RNA sequence (fastq) and methylation array (idat) data for 20 participants. Patient characteristics are listed in Table S1. Table S2 lists the differentially methylated probes (DMPs), comparing patients with MetS and controls. Table S3 describes the functional enrichment of genes under hyper- and hypomethylation. Table S4 presents the differentially expressed genes (DEGs). Table S5 describes the functional enrichment of the DEGs, using the DisGeNET gene sets. Table S6 lists the genes with significant correlations between their expression and DNA methylation. Table S7 describes the integrated functional network genes and pathways. List of Tables Table S1. Demographics and characteristics of study population Table S2. List of differentially methylated probes (DMPs) in MetS compared to control Table S3. List of functional enrichment analysis of genes with hyper/hypo methylated in MetS compared to control. Table S4. List of differentially expressed genes (DEGs) in MetS compared to control. Table S5. List of functional enrichment analysis of DEGs using DisGeNET gene sets. Table S6. List of significantly correlated genes between DNA methylation and gene expression. Table S7. List of integrated functional network genes and pathways.