Metabolic parameters of lumbar muscle fatigue resistance in lower backpain patients and controls
Description
Anthropometric data and changes in aerobic muscle and cardiovascular metabolism during isometric lumbar exercise to exhaustion (Soerensen test). Abbreviations: Group, patients or matched controls; Gender, (male =2, female = 1); Age, years of age; acetyp, insertion/deletion genotype for polymorphism rs1799752 in the gene of angiotensin concertingy enzyme; tenascin, genotype for polymorphism rs2104772 in the tenascin-C gene; Sportsscore, physical activity levels; Duration, time-to-exhaustion [sec]; SorensenT_accomplished, exercise test duration >240 seconds; Best_Stronghand, handgrip strength dominant side [kg]; Best_Weakhand, handgrip strength minor side [kg]; BMI, body-mass index [kg m-2]; Height, body height [cm]; Weight, body weight [kg]; Smoke, regular smoker [1=yes]; Sportsscore_calc, physical activity levels (full calculation); LAC_baseline, blood lactate concentration at baseline [mM]; LAC_Cessation, blood lactate concentration after exhaustion [mM]; LAC_2min_post, blood lactate concentration 2 minutes after exhaustion [mM]; LAC_2minvs0min_post, delta in blood lactate concentration 2 minutes versus immediately after exhaustion [mM]; LAC_2minvsbase, delta in blood lactate concentration after exhaustion versus baseline [mM]; LAC_max_post, maximal blood lactate concentration after exhaustion [mM]; AUC_D_SmO2_Long, AUC for the delta of oxygen saturation in M. longissimus during isometric lumbar exercise [% sec]; AUC_D_tHb_Long, AUC for the delta of total hemoglobin concentration in M. longissimus during isometric lumbar exercise [g dL-1 sec]; AUC_PP, AUC for the delta of peak blood pressure during isometric lumbar exercise [mm Hg sec]; AUC_MAP, AUC for the delta of mean arterial blood pressure during isometric lumbar exercise [mm Hg sec]; AUC_HR, AUC for the delta of heart rate during isometric lumbar exercise [beats x 60]; AUC_p_t_SmO2_Long, AUC for the delta of oxygen saturation in M. longissimus per time during isometric lumbar exercise [%]; AUC_p_t_tHb_Long, AUC for the delta of total hemoglobin concentration in M. longissimus per time during isometric lumbar exercise [g dL-1]; AUC_p_t_PP, AUC for the delta of peak blood pressure during isometric lumbar exercise [mm Hg]; AUC_p_t_MAP, AUC for the delta of mean arterial blood pressure during isometric lumbar exercise [mm Hg]; AUC_p_t_HR, AUC for the delta of heart rate per time during isometric lumbar exercise [beats per minute]; Fat_longissiumus, thickness in fat of longissimus muscle [cm]; Fat_multifidi, thickness in fat of multifidus muscle [cm]; Fat_Mean, thickness in fat of lumbar muscles [cm].
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Steps to reproduce
Chronic low-backpain patients and physical activity-, age-, and BMI- matched controls conducted a Soerensen-Bjering test comprising isometric lumbar extensor exercise to exhaustion with concomitant monitoring of strain to the aerobic metabolism in M. longissimus and cardiovascular metabolism. Pain and habitual physical activity levels were estimated based on validated questionnaires. Genotyping was performed on genomic DNA with polymerase chain reactions for either of the three genotypes of rs1799752 (i.e. II, ID or DD), and rs2104772 (i.e. AA, AT or TT).