COVID-19 isolation and frailty

Published: 23 August 2021| Version 1 | DOI: 10.17632/wtm8vn55ds.1
Matteo Briguglio


In the post-COVID-19 era, the saturation of health services may only be the tip of the iceberg in relation to the restriction-derived burden of frailty. During confinement, the diminished state of resilience in elderly people may have worsened all age-associated conditions, such as a mild high blood pressure, glucose intolerance, basal immune dysfunction, inflammaging, and mental liability with anxiety-depressive traits. The dynamics of “frailty” renders its transition to a worse level more common than improvement, and this COVID-19 pandemic may have spin the loop of a decline of decreasing functional ability, increasing frailty, greater risk of traumatic falls, and higher hospital admissions for fragility fractures in the near future. The dataset was used to write the opinion article "Consequences for the Elderly After COVID-19 Isolation: FEaR (Frail Elderly amid Restrictions)", which was published by the Journal Frontiers in Psychology in 2020. It has been also used for the research article "How SARS-CoV-2 Pandemic Changed Traumatology and Hospital Setting: An Analysis of 498 Fractured Patients", published in 2021 by the Journal of Clinical Medicine.



IRCCS Istituto Ortopedico Galeazzi


Frailty, Bone Fragility, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19