A double blind, randomized, placebo-controlled pilot trial of individualized homeopathic medicines in heavy menstrual bleeding

Published: 25 March 2026| Version 1 | DOI: 10.17632/ww3ykdghpk.1
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Description

This double-blind, randomized, placebo-controlled pilot trial evaluated the efficacy of individualized homeopathic medicines (IHMs) in women with heavy menstrual bleeding (HMB). While IHMs did not demonstrate a statistically significant reduction in menstrual blood loss (PBAC) in the primary analysis, consistent trends toward improvement were observed, particularly in per-protocol and sensitivity analyses. Notably, IHMs produced a significant and robust improvement in quality of life (MMAS) compared to placebo. The intervention was safe, with no reported adverse events. These findings suggest that individualized homeopathy may serve as a beneficial, non-invasive adjunct in HMB management, particularly in enhancing patient-centered outcomes, though larger trials with objective measures are needed to confirm efficacy.

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Placebo, Homeopathy, Randomized Controlled Trial

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