Gatto F_Supplementary Figure 1

Published: 17 November 2022| Version 1 | DOI: 10.17632/x2d2wcv7kg.1
Federico Gatto


Growth hormone (GH) and chromogranin A (CgA) mRNA expression evaluated in 8 primary cultures of GH- or GH/PRL-secreting pituitary adenomas, compared to 8 samples from clinically non-functioning pituitary adenomas (NFPAs).


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To check the purity of our primary cultures and to further validate our method, GH and chromogranin A (CgA) mRNA expression was investigated in freshly isolated cells from 8 out of 23 tumors included in the study (in which enough material was available). The data were compared with the results obtained in freshly isolated cells of 8 clinically non-functioning pituitary adenomas (NFPAs), randomly selected from our biobank, based on cDNA availability.


Ospedale Policlinico San Martino, Erasmus MC, Universita degli Studi di Genova


Messenger RNA, Somatostatin, Pituitary, Growth Hormone, Pituitary Tumor, Somatostatin Receptor Agonist, Pituitary Disorder, Acromegaly