Congenital Chagas Disease: qPCR and Gold Standard Diagnostic Algorithm tests in a cohort of patients
Published: 19 December 2024| Version 1 | DOI: 10.17632/x36vmxdv6h.1
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The study was developed in the National Institute of parasitology (NIP), Argentina, and Pan-American Health Organization/ Word Health Organization Collaborating Center for Chagas Disease. Between July 2014 and May 2018, a prospective cohort study was carried out with 499 children born to seropositive for T. cruzi infection included. The performance of qPCR techniques was compared with the gold standard diagnostic algorithm for Congenital Chagas disease (CCD-GS), which comprises performing more than one parasitological test on children from birth until nine months of age, and serology from ten months of age.
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Instituto Nacional de Parasitología Dr. Mario Fatala Chaben, ANLIS Dr. Carlos G. Malbran
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Molecular Diagnostics, Clinical Microbiology