Data for: Development, validation and implementation of radio-HPLC methods for the P2X7-receptor-targeted [11C]GSK1482160 radiopharmaceutical

Published: 21 September 2018| Version 1 | DOI: 10.17632/xcj62pwcmy.1
Contributors:
Mark Green,
Carmen Wissmann,
Mingzhang Gao,
Qi-Huang Zheng,
Min Wang

Description

Supplementary Material Table 1. Experimental data used in the determination of Limit of Detection (LOD) and Limit of Quantitation (LOQ), based on the signal-to-noise ratio. Supplementary Material Table 2. Experimental data used to calculate method accuracy, ex- pressed as % Recovery, at three concentration levels, for both components, the desmethyl- GSK1482160 precursor and GSK1482160. Supplementary Material Table 3. Experimental data of ten replicate standard injections (with the standard concentration of 10.0 nmol/mL), used in the precision-repeatability calculations. Supplementary Material Table 4A. Experimental data used to assess linearity in the radiophar- maceutical sample concentration range (of 1.0 nmol/mL to 15.0 nmol/mL) for both components GSK1482160 and desmethyl-GSK1482160 precursor. Supplementary Material Table 4B. Linearity results for standard solutions at five concentration levels: 10%, 25%, 50%, 100%, and 150% of nominal sample concentration.

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