Gradual changes within long-lived influenza virus-specific CD8+ T cells underpin the loss of highly-functional clonotypes in older adults
Description
Supplemental Table 2 Carolien E. van de Sandt (1), Hayley A McQuilten (1), Thi H O Nguyen (1), Sophie A Valkenburg (1), Emma J Grant (2,3), Sneha Sant (1), Jamie Rossjohn (3,4), Stephanie Gras (2,3), Jane Crowe (5) and Katherine Kedzierska (1). 1 Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia 2 Viral and Structural Immunology Laboratory, Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC 3086, Australia. 3 Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia 4 Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, CF14 4XN, UK 5 Deepdene Surgery, Deepdene, Victoria 3103, Australia File contains counts of influenza A2/M1(58-66) specific CD8+ T cell clonotypes sampled from adults (n = 3) and older adults (> 60 years of age, n = 4) collected on 2-3 occasions spanning 7-12 years.