Genealogical trees of five Dominican families with non-syndromic cleft lip and/or palate with autosomal dominant inheritance

Published: 12 June 2024| Version 1 | DOI: 10.17632/xjgbnvk9kg.1


Family trees of five Dominican families are presented with the following criteria: Dominican males and females of all ages with an initial diagnosis of non-syndromic cleft lip and/or palate and autosomal dominant inheritance and subjects of known Dominican origin for at least three generations.


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Regarding the methodology for preparing them: 1. Clinical and population information was collected from affected and unaffected individuals with cleft lip and/or palate in each family, spanning at least three generations. 2. Specialized software, Family History Tool, was used for the construction of genealogical trees. 3. Standard conventions were followed for the representation of individuals in genealogical trees: squares for males, circles for females, and filled shapes for affected individuals. This included the numbering of generations (I, II, III) and the identification of each individual within their generation (1, 2, 3...). Individuals were connected using lines to represent kinship relationships: horizontal lines for marriages/unions and vertical lines for descent. Relevant information was added, such as age at diagnosis, type of cleft, and other pertinent clinical data, below each affected individual. The trees were carefully reviewed to ensure the accuracy of the information and visual clarity, and finally, the genealogical trees were exported as high-resolution images in PNG format for inclusion in the manuscript.


Universidad Nacional de Colombia, Universidad Nacional Pedro Henriquez Urena


Inheritance, Cleft Lip, Cleft Palate, Genealogical Numbering System, Pedigree


Fondo Nacional de Innovación y Desarrollo Científico–Tecnológico

FONDOCyT No. 2018-19-2A5-236