Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases- Tarke et al., 2021

Published: 21-01-2021| Version 1 | DOI: 10.17632/xjzk7gg8b7.1
Contributor:
Alba Grifoni

Description

SUPPLEMENTARY TABLE LEGENDS Table S2. HLA typing for class I and class II molecules in the donor cohort. Predicted epitopes were synthesized based on the most frequent 28 HLA class I alleles in the general population. The donors selected for further testing for class I and/or class II epitope identification are indicated. Related to Fig. 4-5. Table S5. List of CD4+ T cell epitopes identified in this study and their predicted HLA restriction(s). A total of 280 15-mer epitopes were identified by AIM assay and encompassed the 9 dominant SARS-CoV-2 antigens for CD4+ T cells. Related to Fig. 5. Table S6. List of all class II peptides and class I predicted peptides for each of the 28 HLA class I alleles considered in this study and the relative magnitude of response per donor. Related to Fig. 4-5. Table S8. List of CD8+ T cell epitopes identified in this study and the HLA restrictions. A total of 523 class I epitopes were identified by AIM assay and encompassed the 8 dominant SARS-CoV-2 antigens for CD8+ T cells. Related to Fig.4.

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