Table 1: Summary of mean Sciatic Function Index (SFI)
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From Table 1: it was observed that the sciatic nerve index increased significantly in the group 2(untreated ) aa day after the injury compared to group 1, 3 and 4 . the Negativity observed in group 2,3 and 4 indicated the extent of injury on the sciatic nerve . The Sciatic nerve index increase significantly inn group 2 a day, 1 week , 2weeks and 3weeks without any significant recovery . the data described the sciatic index of animals in each group , From Table 1: it was observed that the sciatic nerve index increased significantly in the group 2(untreated ) aa day after the injury compared to group 1, 3 and 4 . The Negativity observed in group 2, 3 and 4 indicated the extent of injury on the sciatic nerve . The Sciatic nerve index increase significantly inn group 2 a day, 1 week, 2weeks and 3weeks without any significant recovery .In group 3, the sciatic nerve index increases significantly a day after induction, however a significant reduction was observed week 1, week2 and week 3. The negativity seen in group 3 is moving towards positivity. Hence, it indicated the sciatic nerve index decrease significantly compared to group 2. In group 1 , positive sciatic nerve index was observed which shows that there was no injury at all . Group 4 shows a significant increase A day after the induction of injury on sciatic nerve, however a significant decrease at end of three week . All data are expressed as mean and standard error of mean, P<0.05. From Table 2, the group 1 has 100% recovery which indicates no injury .group 2 show a significant decrease compared to group,p<0.05. a significant increase was observed in group 3 compared to group 2 but not as high as found in group 1. Group 4 shows a significant increase compared to both group 3 and 2.
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Functional Analysis of Sciatic Foot/Nerve Index (SFI) Capture and analysis of foot prints images of the lower feet were captured using a graph sheet and stamp ink. The graph sheet was imprinted with stamp ink as the rabbit walk inside the corridor of the walking tract apparatus. This was allowed to dry and measurements were taken (nearest millimeter). Data concerning each animal were individually identified, so as to allow follow-up over time. The parameters measured for both normal (N) and operated (E) feet were footprint’s length (PL or longitudinal distance between the tip of the longest toe and the heel), total toes spreading (TS or cross-sectional distance between the first and fourth toes) and intermediate toes spreading (IT, or cross-sectional distance between the second and the third toes). The formula used for SFI calculation was the one proposed by Bain et al. (Dellon and Mackinnon, 1989), as follows: SFI=-38.899 EPL/NPL-NPL/NPL+109.5 ETS/NTS-NTS/NTS+13.3 EIT/NIT-NIT/NIT-8.8 Where; NPL = normal longitudinal distance between the tip of the longest toe and the heel EPL = operate longitudinal distance between the tip of the longest toe and the heel NTS = total toes spreading or cross-sectional distance between the first and fourth toes of the normal hind EPL = total toes spreading or cross-sectional distance between the first and fourth toes of the operated hind NIT = intermediate toes spreading or cross-sectional distance between the second and the third toes of the normal hind EIT = intermediate toes spreading or cross-sectional distance between the second and the third toes of the operated hind Calculation of Injury Index Day 1 injury index D1 = (B-A) B= SFI before injury A= SFI after injury Day 21 injury index D21 = (B-T) B= SFI before injury T= SFI after treatment Calculation of the Recovery Index Recovery Index = (D1-D21) D1= Day 1 Injury Index D21= Day 21 Injury Index Calculation of the Percentage Recovery PR= (B-A)-((B-T))/((B-A))*100/1 PR= Percentage Recovery B= SFI before injury A= SFI after injury T= SFI after treatment D1= Day 1 Injury Index D21= Day 21 Injury Index Statistical Analysis Data of sciatic function index test were statistically evaluated using SPSS 20.0 software and the results expressed as Mean ± Standard Error of Mean at P < 0.05 indicating a statistical significance between the rabbits.