Supplemental Figure 2

Published: 15 July 2022| Version 1 | DOI: 10.17632/xkr93dz6vr.1
Ananda Fontoura, Awais Javaid, Víctor Sáinz De La Maza Escolà, Nia Salandy, Susan Fubini, Ester Grilli, Joe McFadden


Effects of environmental conditioning and dietary organic acid and pure botanical supplementation on in vivo intestinal permeability measure by (A, C) Cr concentrations in plasma and (B, D) area-under-the-curve (AUC) after a pulse dose of Cr-EDTA in pregnant multiparous lactating Holstein cows. Figures A and B are relative to Cr-EDTA challenge on day 3 of heat stress conditioning. Figures C and D are relative to Cr-EDTA challenge on day 13 of heat stress conditioning. Cows were randomly assigned to one of four treatments at enrollment: unsupplemented thermoneutral conditions (TN-Con, n = 12), heat-stress with no organic acids and pure botanicals (OA/PB) supplementation (HS-Con, n = 12), thermoneutral conditions pair-fed to HS-Con (TN-PF, n = 12), HS supplemented with OA/PB (75 mg/kg of body weight [BW]; AviPlus R; VetAgro S.p.A., Italy; HS-OAPB, n = 10). Control cows (not supplemented with OA/PB) received a matching dose of the lipid matrix. ┴HS-Con vs. TN-Con, Treatment × Time, P < 0.15. *HS-Con vs. TN-PF, Treatment × Time, P < 0.15. ‡TN-PF vs. TN-Con, Treatment × Time, P < 0.15. †HS-Con vs. HS-OAPB, Treatment × Time, P < 0.15.



Cornell University


Dairy Cattle