Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster - Miguel-Escalada et al.

Published: 10 August 2022| Version 1 | DOI: 10.17632/xnckzpgxj8.1
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Description

This repository contains processed files from 1) mouse single-cell datasets (scRNA-Seq and scATAC-Seq from E10.5 pancreatic multipotent progenitors (MPCs) and scATAC-Seq from E13.5 pancreas) and 2) human MPCs H3K27ac, PTF1A and Mediator ChIP-Seq (BED and BigWig files). Raw sequencing reads have been deposited in the Gene Expression Omnibus (GEO) public repository at NCBI (https://www.ncbi.nlm.nih.gov/geo/) under accession number GSE183674.

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Institutions

Centre de Regulacio Genomica

Categories

Developmental Biology, Diabetes, Enhancer, Chromatin Immunoprecipitation, Endocrine Pancreas, Pluripotent Stem Cell Differentiation, Single-Cell RNA Sequencing

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