Magnetic resonance imaging characterisation of an α-synuclein model of Parkinson’s disease
Description
This folder contains data used in the paper: Magnetic resonance imaging characterisation of an α-synuclein model of Parkinson’s disease Chirine KATRIB, Hector HLADKY, Kelly TIMMERMAN, Nicolas DURIEUX, Nathalie DUTHEIL, Erwan BEZARD, David DEVOS, Charlotte LALOUX and Nacim BETROUNI. To be pubished in European Journal of Neuroscience (Update October 2024). Please contact the corresponding author if you need further details about this work and data Nacim Betrouni, PhD French Natinal Institute of Health and Medical Research (INSERM) Lille NeuroScience & Cognition nacim.betrouni@inserm.fr
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The study was an MR characterisation of the AAV alpha-synuclein rat model of Parkinson's disease. It included longitudinal MR data acquired at three times: 2 weeks, 10 weeks and 18 weeks post injection. It included also histological evaluations The animals were organised into two groups: the active alpha-synuclein group (ASYN) and a control group (CTRL). The repository contains multimodal magnetic resonance images and histology data. The study was organised into two acquisitions. in the first (Folder: AAV_R2StarStudy), T2w and T2* images were acquired, while in the second (Folder: AAV_fMRIStudy), T2w and Resting state fMRI were acquired. Histology folder contains the staining images and the alpha-synuclein quantifications.
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Association France Parkinson