Hydroxyurea-induced Melanonychia: A Rare Case Report and Review of the Literature

Published: 18 September 2023| Version 1 | DOI: 10.17632/y9pbz7682t.1
Michael Buontempo,


Supplemental Table S1: Hydroxyurea-Induced Melanonychia in Patients with Thrombocytosis This table provides a comprehensive overview of case reports on patients diagnosed with thrombocytosis and treated with hydroxyurea, detailing the emergence of melanonychia—a brown to dark pigmented band on the nails—as a side effect. The parameters observed and presented in this table include the author and publication year, patient demographics (gender and age), the hydroxyurea dosage regimen, the duration of treatment before melanonychia onset, specific nail findings, and whether hydroxyurea therapy was discontinued. Special notes regarding the diagnosis or unique clinical manifestations have been highlighted where relevant. This supplemental information serves to give readers a more in-depth understanding of the prevalence and presentation of hydroxyurea-induced melanonychia in clinical settings and complements the manuscript's primary findings and discussion.



NYU Langone Health, Hackensack Meridian Health


Dermatology, Case Report