Data for: Follow up Study: the Influence of rTMS with High and Low Frequency Stimulation on Motor and Executive Function in Parkinson’s disease.
Conclusions In this study we confirmed the importance of the intensity of the treatment with rTMS, which may differ according to the frequency of stimulations. The effect of rTMS develops slowly and its effect is maintained for months. We observed a strong age dependency in the effect of rTMS, which may indicate the need for more frequent treatment with rTMS in patients over 65 yrs than in the younger group of age. The longevity of the effect is not only, explained by the modification of the brain plasticity or the induction of the dopamine release in the striatum by rTMS. Although, the role of the prolonged elevation of BDNF and production of progenitor cells in the brain may be an important mechanism in the effect of rTMS.