The Binding Prediction Model of The Iron-responsive Element Binding Protein and Iron-responsive Elements

Published: 28 Jan 2020 | Version 1 | DOI: 10.17632/yfxthhhdtp.1
Contributor(s):

Description of this data

Iron is essential to fulfilling an indispensable role in the biological process in human physiology. Various proteins were known involved in iron metabolism. One of the proteins called iron-responsive element binding protein (IRP) which acts as master iron of cellular iron homeostasis. There are two IRP known to date, which is: IRP1 and IRP2. Previous studies showed IRP bind to iron-responsive elements (IRE) located in 5’-UTR of the transferrin receptor 1. The interaction of IRP/IRE is well studied through many years to find a better treatment for the cellular disorder in iron metabolism. However, the structural differences of both IRP and the binding prediction model of IRP/IRE remain unclear. This dataset provides structure predictions of IRP/IRE by using reliable bioinformatics tools .

Experiment data files

  • Binding prediction model
    Cite
  • IRE structure prediction
    Cite
  • IRP and IRE fasta
    Cite
  • IRP structure prediction
    Cite
  • Molecular Interaction of IRP and IRE
    Cite

Related links

Latest version

  • Version 1

    2020-01-28

    Published: 2020-01-28

    DOI: 10.17632/yfxthhhdtp.1

    Cite this dataset

    Ramanto, Kevin Nathanael; Parikesit, Arli Aditya (2020), “The Binding Prediction Model of The Iron-responsive Element Binding Protein and Iron-responsive Elements”, Mendeley Data, v1 http://dx.doi.org/10.17632/yfxthhhdtp.1

Statistics

Views: 72
Downloads: 0

Categories

Protein-RNA Interaction, Computational Bioinformatics, Molecular Docking, Protein Structure Prediction

Licence

CC BY 4.0 Learn more

The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.

What does this mean?
You can share, copy and modify this dataset so long as you give appropriate credit, provide a link to the CC BY license, and indicate if changes were made, but you may not do so in a way that suggests the rights holder has endorsed you or your use of the dataset. Note that further permission may be required for any content within the dataset that is identified as belonging to a third party.

Report