Proteome-Wide Bioinformatic Annotation and Functional Validation of the Monotopic Phosphoglycosyl Transferase Superfamily
Description
Optimized Sequence Similarity Networks (SSNs) of the SmPGT family allowing for functional annotation of clusters as validated in the published work. Datasets S1-S4 and S6 can all be visualized using Cytoscape. Dataset S1 is the network file for the E-value 1x 10-61, 100% representative node SmPGT network. Dataset S2 is the Cytoscape session file, with applied coloring, of the E-value 1x 10-61, 100% representative node SmPGT network. Dataset S3 is the network file for the E-value 1x 10-71, 100% representative node SmPGT network. Dataset S4 is the Cytoscape session file, with applied coloring, of the E-value 1x 10-61, 100% representative node SmPGT network. Dataset_5 is the Genome Neighbourhood Network of the E-71 SSN, viewable as diagrams on the EFI-EST server. Dataset_S6 is Genome Neighbourhood Diagrams of the clusters from the E-71 SSN, with the clusters as hub-nodes and neighbouring Pfam families as spoke-nodes
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Steps to reproduce
See publication doi: https://doi.org/10.1101/2024.07.10.602977
Institutions
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Funding
National Institute of General Medical Sciences
R01 GM131627
National Institute of General Medical Sciences
F32 GM134576
National Institute of General Medical Sciences
F32 GM136023
Imperial College London
Turing Scheme Award