Dataset: Disrupted reinforcement learing during post-error slowing in the stop signal task
Description
fMRI data from "Disrupted reinforcement learning during post-error slowing in ADHD" All files are in NIFTI (.nii) format. All maps are in talairach (+tlrc) space. All directories contain an average anatomic file for display purposes. Directories and contents: maps-main study: Single subject activation maps used as input to ANOVA and correlation analyses (sub-brik#(0-13) = subject#(0-13)). go = response-phase maps (i.e. (1/2)(left+right); det = error detection maps; pes = post-error slowing maps e.g. "det-adhd" refers to error detection maps for all ADHD subjects - sub-brik #0 = subject #1 ... sub-brik #13 = subject #14. maps-replication: Single subject activation maps (as above) for replication study. Table 1 ANOVAS: Raw ANOVA output corresponding to Table 1 (and Supplementary Figure 1) for TD, ADHD, and group difference analyses (t* and estimate maps for Detect and Post-error slowing), and cluster-thresholded ANOVA outputs. Files (sub-briks): TD 0, 1: Full model estimate, F-stat(4,65) 2, 3: Fixate estimate, t*(13) 4, 5: Go estimate, t*(13) 6, 7: Stop-Go estimate, t*(13) 8, 9: Detect estimate, t*(13) ADHD 0-9: same as above TD-thresholded 0-4: Thresholded maps of %BOLD estimates during Fixate, Go, Stop-Go, Detect, and PES ADHD-thresholded 0-4: same as above diffs 0, 1: Group difference estimate and t*(26) during Detect 2, 3: Group difference estimate and t*(26) during PES diffs-thresholded 0: Cluster thresholded group difference in %BOLD during Detect 1: Cluster thresholded group difference in %BOLD during PES Table 2 ... Table 7: Raw correlation outputs (e.g. "SN-Det-go-td" refers to SN seed activity during error detection correlated with response-phase (i.e.go) activity in TD group) corresponding to Tables 2-7 (and Supplementary Figures 2-5). Extra sub-briks are appended to correlation output files, one at the beginning and one at the end. The first appended sub-brik contains a cluster-thresholded map of B1 estimates, and the last appended sub-brik contains the raw, signed correlation coefficient 'r' correlation file sub-briks 0: Thresholded map of B1 (slope term) estimates 1: Baseline offset (B0) estimate 2: Baseline offset t*(12) 3: Slope (B1) estimate 4: Slope t*(12) 5: Full F-stat (1,12) 6: Squared correlation (r^2) 7: Unsigned correlation coefficient (r) Data corresponding to confirmatory analyses portrayed in Supplementary Figures 6 and 7 are identical to the thresholded corelation maps in substantia nigra (Table 3) and raphe nucleus (Table 4).
Files
Steps to reproduce
see methods