A study of Virus-induced changes in mRNA secondary structure uncover cis-regulatory elements that directly control gene expression. Mizrahi et al.

Published: 27 October 2018| Version 2 | DOI: 10.17632/yvgd6fd2xs.2
Contributor:
Orel Mizrahi

Description

Unraveling cis-regulatory elements by mapping changes in mRNA structure for that reason, we measure the changes in mRNA structure using DMS-MaPseq libraries between uninfected and HCMV infected cells, and found dozens of regions in mRNAs that significantly change their structure, and have a direct role in gene expression regulation.

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Molecular Biology, RNA Structure, Regulatory Element

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