Protective effect of vitreous against hemoglobin neurotoxicity

Published: 30 May 2018| Version 1 | DOI: 10.17632/yyk22tn93y.1
Jing Chen-Roetling,
Kathleen Regan,
Raymond Regan


Hypothesis: Vitreous protects neurons from hemoglobin (Hb) toxicity. Model: Primary cortical cell cultures (murine); cultures treated with Hb 10 micromolar alone or with bovine vitreous or vitreous components. Outcome measures: Lactate dehydrogenase (LDH)release, propidium iodide fluorescence staining intensity, culture malondialdehyde (MDA), culture iron.