Multidrug-resistant Klebsiella sp. is the main etiological agent of urinary and respiratory tracts infections in infants at southeastern Mexico
Description
The purpose of the work was to determine the Klebsiella species affecting hospitalized infants at southeastern Mexico, their susceptibility profile to antimicrobials, the resistance phenotype, and the presence of ESBL enzymes. Methodology: From 2015 to 2020, a total of 794 records of bacteriological cultures positive to Klebsiella spp. were included. The frequencies of bacterial species, the biological material from which they were isolated, the age groups affected, the antimicrobial susceptibility profiles, the resistance phenotype, and the detection of ESBL enzymes were obtained. Results: K. pneumoniae subsp. pneumoniae was the most frequent bacteria isolated from urine, blood and bronchial aspirate samples. Most of them were resistant to beta-lactams and cephalosporins, in addition to exhibiting the MDR phenotype associated with the presence of ESBL enzymes. The susceptibility of the strains to meropenem and ertapenem indicates that carbapenems are the treatment alternative to combat these nosocomial infections in infants at southeastern Mexico.