Data from: Sub-cone visual resolution by active, adaptive sampling in the human foveola
Description
Cone mosaic images, cone coordinates, retinal locations (PCD, CDC and PRL) and eye motion trajectories are related to: Witten et al., Sub-cone visual resolution by active, adaptive sampling in the human foveola, eLife (2024), https://doi.org/10.7554/eLife.98648.1 A MATLAB code that can be used for plotting the data on the original image is provided. Abstract: The foveated architecture of the human retina and the eye’s mobility enable prime spatial vision, yet the interplay between photoreceptor cell topography and the constant motion of the eye during fixation remains unexplored. With in vivo foveal cone-resolved imaging and simultaneous microscopic photo stimulation, we examined visual acuity in both eyes of 16 participants while precisely recording the stimulus path on the retina. We find that resolution thresholds were correlated with the individual retina’s sampling capacity, and exceeded what static sampling limits would predict by 18 %, on average. The length and direction of fixational drift motion, previously thought to be primarily random, played a key role in achieving this sub-cone diameter resolution. The oculomotor system finely adjusts drift behavior towards retinal areas with higher cone densities within only a few hundred milliseconds to enhance retinal sampling. Additional information about previous scientific projects and ongoing research can be found on our website: https://ao.ukbonn.de/
Files
Steps to reproduce
The dataset contains a README with further information. The data were collected using an adaptive optics scanning laser ophthalmoscope for photoreceptor resolved imaging and simultaneous visual function testing. It has been processed using custom MATLAB code to stabilize and align the videos to be able to track and compare the retinal motion over time. A master reference image was created where each individual cone was labeled in a semi-manual procedure. Further details can be found in the "Methods" section of the associated publication.
Institutions
Categories
Funding
Deutsche Forschungsgemeinschaft
HA5323/5-1
Carl-Zeiss-Stiftung
HC-AOSLO
Novartis Pharma
EYENovative research award
Open Access Publication Fund of the University of Bonn