DATASET FOR FACTOR V LEIDEN IN SUBJECTS WITH PREECLAMPSIA
Agricultural and Biological SciencesUniversity of Ghana School of Medicine and Dentistry, Medical Biochemistry, Korle-Bu, AccraConceptualization, Experimental, Data Analysis, write-up, resources, supervision, funding acquisition
Kwame Adu-Bonsaffoh ,
Medicine and DentistryUniversity of Ghana School of Medicine and Dentistry, Obstetric and Gynecology, Korle-Bu AccraConceptualization, Methodology, Analysis, Proofreading of write-up
Emmanuel AbindaoUniversity of Ghana School of Medicine and Dentistry, Physiology Department, Korle-Bu, AccraInvestigation, Experimental, Analysis
Grace NarhUniversity of Ghana, Biochemistry Department, Legon, AccraExperimental, Data Analysis
Diana TettehNational Diabetes Research Center, Korle-Bu, AccraInvestigation, Experimental
Medicine and DentistryKorle-Bu Teaching Hospital, Child Health, AccraInvestigation, Experimental
Diana MorveyClinical Documentation Specialist, Culver State, CaliforniaExperimental, Investigation
Biochemistry, Genetics and Molecular BiologyKNUST, Kumasi, GhanaInvestigation, Experimental
Isaac QuayeRegent University of Science and Technology, Allied Health, AccraConceptualization, Resources, Data Analysis, Proofreading
Description of this data
In Ghana, there is limited information regarding factor V Leiden polymorphism on the pathogenesis of preeclampsia (PE) and its associated outcomes; hence, the focus of the current study. Eighty-one (81) consented subjects were recruited after ethical clearance was obtained and structured questionnaire administered to them. Routine blood chemistry and characterization of Factor V Leiden were obtained for subjects. We found FVL mutation much more in PE and hypertensive patients. FVL exon 10 were 0.67 and 0.33 for G and A alleles respectively. There was an absence of FVL mutation in exon 8 in the current study. Increased white blood cells, increased uric acid and a three – fold increment of AST / ALT ratio were observed among PE cases when stratified by FVL exons (exon 8 and 10). This study was the first to report baseline FVL genotypic and allelic frequencies as well as relating clinical variables with it.
Experiment data files
New folderFVL exon 8 profile and clinical variables of the study population.
Cite this dataset
Ababio, Grace; Adu-Bonsaffoh , Kwame; Abindao, Emmanuel; Narh, Grace; Tetteh, Diana; Botchway, Felix; Morvey, Diana; Neequaye, Jonathan; Quaye, Isaac (2019), “DATASET FOR FACTOR V LEIDEN IN SUBJECTS WITH PREECLAMPSIA”, Mendeley Data, v1 http://dx.doi.org/10.17632/zvbbtby75p.1
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The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.