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- Interobserver Variability in Intraoperative Classification of Acute Appendicitis and Postoperative Antibiotic ManagementAcute appendicitis is among the most common diseases requiring emergency surgery. Despite its high prevalence, AA remains incompletely understood, and optimal management continues to be debated and refined. The severity of the disease is currently classified by the macroscopic appearance of the appendix during surgery as either phlegmonous, gangrenous, or perforated (with or without a periappendiceal abscess), In cases of complex appendicitis (i.e., gangrenous or perforated) 1–5 days of postoperative antibiotics are recommended, whereas simple appendicitis (i.e. phlegmonous) is treated with perioperative antibiotics alone. Consequently, the operative findings determine the postoperative antibiotic management, and thus, the biases and experience level of the surgeon could have important implications for patient outcomes. The goal of the current study was to examine the interobserver variability in the classification of Acute Appendicitis severity and to examine the impact of the classification on postoperative antibiotic choice. The study was designed as a multicentre cross-sectional inter-rater reliability study. Video recordings of 30 laparoscopies with a duration of 20 seconds each for suspected appendicitis were shown to 89 surgeons and surgical trainees at seven different Danish hospitals between January 2024 and May 2024. Each video segment was followed by two multiple-choice questions, which the participants answered anonymously on a study form. The participants were asked to categorize the appendix as either normal, phlegmonous, gangrenous, perforated without an abscess, or perforated with an abscess. Answers were further categorized into “normal appendix or appendicitis” (Category 1) and into “complex appendicitis or not” (Category 2). Interobserver agreement was moderate for distinguishing a normal appendix from appendicitis (κ = 0.72, 95% CI 0.61–0.85) and for identifying complex appendicitis (κ = 0.66, 95% CI 0.52–0.80). Agreement regarding postoperative antibiotics was high: 96% for phlegmonous, 81% for gangrenous, and 99.7% for perforated appendicitis.
- Static magnetic field-driven optimization of Ti6Al4V lattice architectures fabricated by laser powder bed fusion This dataset supports the experimental and microstructural analysis presented in the study titled “Static magnetic field-assisted LPBF of Ti6Al4V lattice structures with homogenized microstructure, defect evolution, and enhanced mechanical performance.” It includes raw and processed data from uniaxial compression tests, micro-computed tomography (Micro-CT), Electron Backscatter diffraction (EBSD), and Transmission electron microscopy (TEM) performed on both OOCS and HRS lattice structures fabricated using laser powder bed fusion (LPBF). The repository also contains high-resolution figures, mechanical performance metrics, porosity analysis, original microscopy images, and defect quantification maps. These data are intended to support reproducibility, secondary analysis, and future modeling efforts in the field of additive manufacturing and architected materials.
- Common and particular biochemical effects of gadolinium and yttrium in the bivalve mollusc Unio tumidusEnvironmental concentrations of rare earth elements (REEs) are increasing rapidly due to their unique properties and widespread application in modern technologies. Since the biological effects of REEs are expected to be similar to those of essential metals, the goal of this study was to verify the impact of selected REEs on the zinc (Zn) related biochemical characteristics in the bivalve mollusc Unio tumidus. The mussels were treated with gadolinium (GdCl3, 30 nM) and yttrium (YCl3, 30 nM) for 14 days. The accumulation of Gd, Y, Zn (Zn t) in the tissue, level of metallothioneins (total MTSH and Zn-boind ZnMT) as well as the redox state and enzyme activities were analysed in the digestive gland. Molluscs accumulated the excess of Gd in the tissue, unlike Y in the corresponding exposure. Both exposures caused the signs of neurotoxicity indicated as choline esterase activity, and decreased the levels of Zn t, whereas the level of ZnMT was unchanged (Gd-group) or decreased (Y-group). In both exposures, the concentrations of GSH, GSSG, MTSH, NADH, and NAD+, as well as the NADH/NAD+ ratio increased dramatically, while lipid peroxidation (TBARS) decreased, attesting a reductive shift and antioxidant manifestations. Specific effects of the exposure to Gd was decrease in lysosomal integrity and depletion of caspase-3. IBRv2 indicated the higher magnitude of integrated response to Gd. These findings confirm the dependence of Zn functionality on REEs effect and can contribute to the assessment of REEs impact in the areas of concern.
- Whistlers identified in DEMETER measurementsA list of whistlers and their parameters detected in DEMETER satellite burst mode measurements between 2004 and 2010. Whistlers are identified using a Faster R-CNN object detection model and parameters determined using a differential evolution algorithm. For more information see doi:
- Immersive Technologies role in shaping Purchase IntentionDataset contains responses from Indian sub-continent, on constructs like - Immersive technologies (IT), Brand Experience (BE), User Satisfaction (US), Perceived Enjoyment (PE) and Purchase Intention (PI). Plus, ranking of 4 immersive technologies feature: Augmented Reality (AR), Virtual Reality (VR), Gamification (GAM) and Immersive Social Interactions (ISI).
- A century-scale dataset of hydropower stations in mainland China (1909–2025)The hydropower station dataset comprises three components: international data, national data, and supplementary data. The international data are primarily sourced from global hydropower databases such as GEM, GloHydroRes, and GPPD; the national data are collected from official statistics, bulletins, and policy records released by the Ministry of Water Resources and the National Energy Administration; and the supplementary data are compiled from archival investigations, project reports, and peer-reviewed literature, ensuring coverage of small and early hydropower stations. The dataset includes 2,918 hydropower stations across 31 provinces and 11 major river basins in China, covering the period of over 100 years . Since the 2010s, we have systematically integrated multi-source records and standardized attributes such as location, installed capacity, commissioning year, operational status, and reservoir characteristics, which form the core structure of this dataset.
- Engineering Asset Management Challenges
- Supplementary Video material - Event-Driven Workflow Authoring and Reconfiguration for Human–Robot Teaming in Collaborative Disassembly Using Natural Language, aR, and Edge ComputingThis video showcases the functionalities implemented and presented in the paper "Event-Driven Workflow Authoring and Reconfiguration for Human–Robot Teaming in Collaborative Disassembly Using Natural Language, aR, and Edge Computing".
- Soil structure controls the trade-off between soil health and erodibility along cascade-reservoir slopes in a dry-hot valleyTable summarises the descriptive statistics and indicates clear spatial contrasts in soil nutrient status, biological activity, and potential stressors across reservoir segments. Across all samples, SOC ranged from 6.3 to 35.5 g kg⁻¹ with a mean of 17.6 g kg⁻¹, TN ranged from 0.77 to 3.65 g kg⁻¹ with a mean of 1.39 g kg⁻¹, and available phosphorus ranged from 4.5 to 48.7 mg kg⁻¹ with a mean of 15.1 mg kg⁻¹. Soil pH was narrowly buffered between 6.8 and 7.8. Trace metals also exhibited strong spatial gradients: Mn and Zn were dominant, ranging from 579 to 1136 mg kg⁻¹ and from 65 to 371 mg kg⁻¹, respectively, while Pb declined sharply from 211 mg kg⁻¹ at RH to 20 mg kg⁻¹ at RT. Chromium ranged from approximately 88 to 142 mg kg⁻¹. Copper showed pronounced local enrichment, peaking at BHT RT at about 177 mg kg⁻¹ rather than at RH, suggesting strong site-specific controls. Spatial differences were also evident in microbial and biochemical properties. Microbial biomass varied widely, with SMBC ranging from about 118 to 684 mg kg⁻¹ and SMBN from about 2.7 to 70.8 mg kg⁻¹. Enzyme activities differed among segments, and aggregate-size distributions were broadly stable, with silt plus clay remaining close to 6 % and only modest variation in macroaggregate and microaggregate proportions. Seasonal shifts further modified these spatial patterns, but the direction and magnitude of change differed among reservoirs and segments. In BHT, urease activity increased from an average of 0.55 mg g⁻¹ in the dry season to 0.70 mg g⁻¹ in the wet season, whereas NAG declined markedly in the wet season and SAP showed mixed seasonal responses across segments. BG varied strongly among locations, reaching its minimum at WDD RT in the wet season at approximately 0.25 μmol g⁻¹ dw h⁻¹. DOC also showed reservoir- and segment-specific seasonality: concentrations were generally higher in BHT than in WDD and often exceeded 130 mg kg⁻¹, but the wet season did not uniformly reduce DOC, with elevated values observed at RM in BHT. Aggregate-size fractions shifted moderately between seasons in BHT, with macroaggregates averaging about 20 % in the dry season and 18 % in the wet season, while microaggregates remained similar across both periods; aggregate composition in WDD was comparatively stable.
- Thermo–pH dual-responsive nanocarriers enable multiscale-controlled antitumor drug resveratrol release via molecular remodeling and electronic decouplingThis study constructs a complete dataset based on quantum chemical calculations and all-atom molecular dynamics simulations to elucidate the recognition, encapsulation, and stimulus-responsive release mechanisms of resveratrol (RES) in the NP nanocarrier system. The dataset includes optimized geometries and electronic structure information of RES, NP, NPH⁺, and their representative cluster structures, which are used to analyze electrostatic potential distributions and intermolecular interaction characteristics. It also provides the fully equilibrated simulation system at 298 K (System-298K-100ns) for investigating the self-assembly and encapsulation processes under ambient conditions. The Cluster-simulation system and ClusterH⁺-simulation system are designed to simulate the evolution of intermolecular interactions and conformational changes under thermo-responsive and pH-responsive conditions, respectively, in order to clarify the environment-triggered drug release mechanism. All initial files required for production simulations, together with the corresponding GROMACS commands used for data extraction, are provided to ensure reproducibility and data transparency.