Current Biology

The zip files has the analysis code that: detect bouts and half beats, calculate kinematic parameters a categorize the bouts into 13 types using K nearest neighbour. Inside, use Matlab to open and run this script: FreeyMovingBehaviourAnalysis\FreelyMovingBehaviorAnalysis_14_forPaper\makeBoutFiles\freelyMovingKinAnalysisWithBoutCat_31.m It will open a user interface where the user should pick the folder where a behavioural file is (mat file). We provide an example inside the zip file: FreeyMovingBehaviourAnalysis\matFileToUpload\ After the user should click in this folder and the analysis will produce a "bout file" with all the information inside.

Behavioral data for manuscript "Integration of sweet taste and metabolism determines carbohydrate reward" Maria Geraldine Veldhuizen, Richard Keith Babbs, Barkha Patel, Wambura Fobbs, Nils B Kroemer, Elizabeth Garcia, Martin R. Yeomans, and Dana M Small. Summary of paper: Post-ingestive signals related to nutrient metabolism are thought to be the primary drivers of reinforcement potency of energy sources. Here, in a series of neuroimaging and indirect calorimetry human studies, we examine the relative roles of caloric load and perceived sweetness in driving metabolic, perceptual and brain responses to sugared beverages. Whereas caloric load was manipulated using the tasteless carbohydrate maltodextrin, sweetness levels were manipulated using the non-nutritive sweetener sucralose. By formulating beverages that contain different amounts of maltodextrin+sucralose, we demonstrate a non-linear association between caloric load, metabolic response and reinforcement potency, which is driven in part by the extent to which sweetness is proportional to caloric load. In particular, we show that (1) lower calorie beverages can produce greater metabolic response and condition greater brain response and liking than higher calorie beverages and (2) when sweetness is proportional to caloric load greater metabolic responses are observed. These results demonstrate a non-linear association between caloric load and reward and describe an unanticipated role for sweet taste in regulating carbohydrate metabolism, revealing a novel mechanism by which sugar-sweetened beverages influence physiological responses to carbohydrate ingestion.

Dataset collected and analyzed for Longden et al (2017) "Spike burst coding of translatory optic flow and depth from motion in the fly visual system".

An example scripts for running CorticalSim. With these parameters, the cortical MT arrays under normal condition will be generated. To obtain the MT arrays under other conditions, please alter the relevant parameters, which are mentioned in our paper. The user manual of CorticalSim can be found at https://github.com/corticalsim/corticalsim (Tindemans, et al., 2014)

Data and supplemental figures from the publication "Dynamics and Ultradian Structure of Human Sleep in Real Life" by EC Winnebeck, D Fischer, T Leise and T Roenneberg

One-photon calcium imaging data in right CA1 of mice traversing a rectangular track and treadmill run for 10 s. Contact William Mau (wmau@bu.edu) for details.

Datasets and phylogenetic trees (Newick format) for PGLS analyses.

These data contain the average, for each participant, of interval estimates used in the analysis of sense of agency under coercion. The variables are: participant number, experiment number, the type of harm that the participant was delivering as the agent (financial harm or physical pain), and the average interval estimates (in ms) for four key conditions of the experiment, as described in the publication. The data does NOT contain information for individual TRIALS (such as whether the outcome on a specific trial did or did not actually involve harm), only for the average of all trials in each condition. Full data sheets with trial-level information are obtainable from ecaspar@ulb.ac.be.

This file includes two tables showing the results of the optimizations of the 50 candidate models for the ‘conservative’ and ‘phylogenetic’ schemes, fitted to branching and colonisation times of birds of Macaronesia. Data from Valente et al. Current Biology.

RNA seq in wt and b-Trcp1/2 ko MEFs