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Electrospun Tubes were characterized by static and dynamic water contact angles. We provide raw data for pure DegraPol® tubes and for DegraPol® tubes that were emulsion electrospun (water in oil emulsion) where in the small water droplets secretome was dissolved. The secretome had been previously harvested from a co-culture of rabbit adipose-derived stem cells and rabbit Achilles tenocytes in a ratio of 3:1. In addition, we provide transmission data of Fourier Transformed Infrared Spectroscopy (FTIR) assessed spectra, taken from pure electrospun DegraPol® tubes, of emulsion electrospun DegraPol® tubes with incorporated secretome harvested from the rabbit adipose-derived stem cell/rabbit Achilles tenocyte co-culture and of poly (ethylene glycol). Finally, we present adhesion extent data gathered from a rabbit Achilles tendon full transection model. We assessed how much of the tissue adhered to the surrounding tissue in cross sections of the rabbit Achilles tendons three weeks post operation compared to the entire circumference. The experimental groups were a) a 4-strand Becker suture, b) a 4-strand Becker suture with a pure DegraPol® tube, c) a 4-strand Becker suture, an injection of 50 microliter of a secretome harvested from a 3:1-ratio cell culture of adipose-derived stem cells:rabbit Achilles tenocytes, and a DegraPol® tube releasing such secretome, and d) the non-treated healthy rabbit Achilles tendons as a control.

This study discovered that the OTUD5–MAVS axis is specifically overexpressed in the mononuclear macrophage subset 11 of patients with primary biliary cholangitis (PBC). These findings may offer a novel therapeutic avenue for targeting the mitochondrial antiviral signalling pathway. The objective of this study was to identify key immune cell subsets through single-cell sequencing technology, thereby establishing the molecular basis for precision immunotherapy tailored to macrophage subtypes. The constructed immune cell infiltration profile will serve as a crucial reference for the clinical differential diagnosis and personalized immune monitoring of PBC. Additionally, this study provides novel biomarkers and targets for the development of small-molecule inhibitors for patients with PBC.

This repository includes supplemental data from our study "Thermogenic gene expression in human neck adipose tissue in relation to circulating and local thyroid hormone levels".

This dataset contains several tar files with model output. One tar file contains model output colocated with buoy observations. The model is for the Barents Sea region. The model is WAVEWATCH III(R) (Tolman 1991, WW3DG 2019). The buoy data were north of Svalbard. The model runs and comparisons are described in this report: https://arxiv.org/abs/2508.16755 This report is approved for public release, distribution unlimited (DoD Distribution Statement A). Jie Yu (NRL 7322) and others are preparing a journal submission which also uses this dataset, being based on a subset of the work described in the report (specifically, this April 2024 Barents Sea model, and comparisons to observations). That journal submission will also be approved for public release, distribution unlimited (DoD Distribution Statement A). The tar files with COAMPS2 and COAMPS3 in the file name contain output from two models runs, “COAMPS2” and “COAMPS3”. (“COAMPS1” was a vanilla run with coarser forcing, so there is no reason to share it) COAMPS2 is from WW3 using IC4M9, a S_ice formula that has dependence on ice thickness (h_ice). It is calibrated for a different h_ice dataset than it is being applied to here. Inevitably, there will be systematic differences in the two h_ice products (they both come with major accuracy concerns), and probable need for new calibration. COAMPS3 is from WW3 with IC4M6, an “old fashioned” S_ice formula that has no dependence on ice thickness. It is for a thin cover of frazil and pancake ice. For COAMPS2 and COAMPS3, I provide the model output in three formats. You can choose the format you prefer. There is no need to download all three. • CGRID.E1D.nc : 1d spectra on computational grid in nc format. Big files • trck.E2D.nc : 2d spectra on buoy tracks (bounding points) in nc format. Medium size files • trck.E1D.mat : 1d spectra on buoy tracks (bounding points) in .mat format. Readable by Matlab or Octave. Small files. For COAMPS2, I provide 2 additional files. • CGRID.bulk.nc : nc files with bulk parameters, excluding model spinup period. Includes wave output (wave height, dominant direction, and integrated energy dissipation by sea ice) and regridded model forcing (ice fraction, ice thickness) • CGRID.spinup.nc : nc files with bulk parameters during model spinup. It includes the same parameters that are included in CGRID.bulk.nc, but the wave output should be disregarded, since it is during the spinup (invalid). COAMPS_Apr2024_colocations.tar.gz : this contains the colocations of model Hm0B with values computed from spectra measured by buoys north of Svalbard. Hm0B is the wave height computed from four different frequency bands (other names are "partial wave height" and "band height". The buoy data were provided by Jean Rabault and Malte Muller of the Norwegian Meteorological Service. A README provided in the tar file has additional details. The files are readable using Matlab or Octave. This is a very small tar file.

Data related to the atomistic molecular dynamics study of DMPC membrane and DMSO.

The RaagaDhvani dataset comprises high-quality audio recordings of solo flute renditions representing 11 selected Carnatic ragas: Bhairavi, Bilahari, Hamsadhwani, Saveri, Thodi, Anandabhairavi, Poorvikalyani, Gaanamurthe, Neelambari, Bhauli, and Dwijavanthi. The primary content includes audio data along with derived emotion annotations, augmentation variants, and associated metadata. All recordings were created by Prof. Vidushi Archana Priyadarshini and are released under the Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) license.

Granulomas, the hallmark of tuberculosis (TB) disease, can both restrict Mycobacterium tuberculosis (Mtb) dissemination and impede its clearance. Recent studies indicate that indoleamine 2,3-dioxygenase (IDO1), an immunosuppressive metabolic enzyme, limits infiltration of activated T cells and can contribute to TB disease progression. Treatment with 1-methyl-D-tryptophan (D-1MT), a small molecule inhibitor that restores mTOR signaling, has been shown to improve immune responses Mtb-infected rhesus macaques. Here, we investigated the impact of D-1MT treatment on TB granuloma architecture using 30-plex high-dimensional issue imaging in rhesus macaques. By spatially mapping 13 distinct cell populations, we found D-1MT treatment corresponded with significantly increased infiltration CD8+ T cells into granulomas compared to untreated controls. Notably, these CD8+ T cells expressed markers of cell proliferation and cytotoxicity. D-1MT enhanced CD8+ T cell infiltration throughout the granuloma, with particularly pronounced effects in the myeloid core, where we observed significantly enhanced spatial interactions between macrophages and CD8+, but not CD4+ T cells. Our results demonstrate that: (i) effective intra-granulomatous Mtb control is associated with the close spatial proximity between CD8+ T cells and macrophages, a feature less abundant in uncontrolled pulmonary TB; (ii) IDO1 induction blocks CD8+ T cell infiltration and reduces T cell activation and proliferation; and (iii) therapeutic strategies, including D-1MT, that improve intra-granulomatous killing hold strong translational potential. This repository comprises the image data generated via MIBI-TOF for this study.

Supplementary Table S1. Demographic and clinical information for palmoplantar pustulosis patients. Note: These data were partially reported in our prior publication in Allergy (PMID: 38193274) and are included here for continuity. Supplementary Figure S1. Representative H&E-stained sections from three patients with palmoplantar pustulosis (Patient No. 1–3), showing intraepidermal neutrophilic pustules, compact hyperkeratosis, psoriasiform hyperplasia, and superficial perivascular inflammatory infiltrates. All images at 10× magnification. Scale bar = 200 μm. Supplementary Figure S2. Patient No. 2 with palmoplantar pustulosis (PPP). Serial clinical photographs at (A) baseline (pre-dupilumab, Month 0), (B) Month 18 on dupilumab, and (C) Month 36 on dupilumab, demonstrating sustained control of palmar (upper panels) and plantar (lower panels) involvement. Supplementary Figure S3. Patient No. 10 with palmoplantar pustulosis (PPP). Serial clinical photographs at (A) baseline (pre-dupilumab, Month 0), (B) Month 18 on dupilumab, and (C) Month 36 on dupilumab, demonstrating sustained control of palmar (upper panels) and plantar (lower panels) involvement.

This dataset was created during the first semester of 2025. It consists of 600 synthetic audios generated with the ElevenLabs and Respeecher tools. It includes both audios generated with TTS (text-to-speech) and V2V (voice-to-voice). Specifically, there are 335 audios generated with ElevenLabs, of which 282 correspond to V2V and 53 to TTS; while 265 audios were generated with Respeecher, of which 210 are V2V and 55 are TTS. This results in a total of 492 V2V audios and 108 TTS audios. In terms of gender distribution, 49% of the audios are male voices, while 51% are female voices. The duration of the audios ranges from 8 to 10 seconds, with a sampling rate of 22,050 Hz. Most of the voices correspond to adults (538 out of 600). This dataset can be used for: (1) training synthetic audio classification models, (2) performing external validation of synthetic audio classification models, and (3) applying attacks to audios and verifying the robustness of synthetic audio classification models.

The Saudi Sign Language (SSL) dataset is organized into four folders. The Narrative Storytelling folder contains 6 MP4 videos of personal stories and a retelling of the Pear Story. The Pictures of Basic Vocabulary folder includes 101 JPG and PNG files along with one annotation file providing glosses in both Arabic and English. The Education folder contains 145 short MTS-format videos with a corresponding annotation file in Arabic and English explaining the content, which focuses on Islamic prayer (Salat). The Alphabet folder consists of 35 JPG images of the SSL fingerspelling alphabet and one annotation file with Arabic and English descriptions.