Short-term exposure to 2,3,6,7-tetrachlorocarbazole induces early serum metabolic disturbance and hepatic lipid remodeling in mice
Description
This dataset contains three processed Excel datasets supporting the manuscript entitled Short-term exposure to 2,3,6,7-tetrachlorocarbazole induces early serum metabolic disturbance and hepatic lipid remodeling in mice. Liver lipid library_DDA: Manually curated in-house DDA lipid annotation library built from mouse hepatic samples, including lipid identity, RT, CCS, lipid subclass and MS/MS fragment information for HDMSᴱ lipid identification. Lipid of exposure liver sample-HMDSE: Processed quantitative lipidomics data from DIA(HDMSᴱ) hepatic lipid profiling of mice with 2367-CCZ short-term exposure, covering normalized lipid abundance, fold change, P-value and FDR for differential lipid screening. Metabolomics of exposure serum sample: Processed untargeted serum metabolomics quantitative data derived from identical animal exposure experiment, including metabolite quantification and statistical analysis results. Raw LC-MS instrument .raw files are not deposited here due to oversized file volume and can be obtained from the corresponding author upon reasonable request. These curated datasets support all omics-related results and figure plotting in the original article, enabling full data repeatability of lipid and metabolomic analysis.