Clinical, Demographic, and Nutritional Factors Associated with Infantile and Childhood Phenotypes of Atopic Dermatitis in Yemeni Children: A Cross-Sectional Study

Description

This dataset contains anonymized clinical, demographic, familial, and nutritional data from a cross-sectional study evaluating factors associated with infantile and childhood phenotypes of atopic dermatitis (AD) among Yemeni children. The study included 152 pediatric patients with physician-confirmed atopic dermatitis attending the pediatric dermatology clinic at Al-Sabeen Hospital, Sana'a, Yemen, between March 21, 2023, and December 12, 2024. Patients were classified according to age at disease onset into infantile AD (onset during the first 2 years of life) and childhood AD (onset after 2 years of age). The dataset includes variables related to: demographic characteristics (sex and residence); clinical characteristics (disease presentation and atopic comorbidities); family history of atopy; household smoking exposure; infant feeding practices during the first 6 months of life; complementary feeding history; maternal educational level. The dataset supports the analyses reported in the associated manuscript, including descriptive comparisons between infantile and childhood AD groups and multivariable logistic regression analysis identifying factors associated with childhood AD phenotype.

Steps to reproduce

The dataset was generated from a cross-sectional study of pediatric patients with physician-confirmed atopic dermatitis. Participants were classified according to age at disease onset into infantile AD and childhood AD phenotypes. Data were collected through structured parental interviews and medical record review. Descriptive statistics were calculated as frequencies and percentages. Comparisons between phenotype groups were performed using Pearson chi-square tests or Fisher exact tests when appropriate. Multivariable binary logistic regression was performed with childhood AD phenotype as the outcome and infantile AD as the reference category. The regression model included sex, family history of atopy, infant feeding pattern during the first 6 months, household smoking exposure, and semisolid feeding history. Analyses were performed using IBM SPSS Statistics version 22.0.

Institutions

• Ibb University

  Ibb Governorate, Ibb

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