Untargeted metabolomics - TINMAN

Published: 23 April 2024| Version 1 | DOI: 10.17632/38z7h96km4.1
Contributors:
Josaura Fernandez Sanchez,
,

Description

Stool samples before and after prolonged (more than 2 weeks) antibiotic treatment were obtained from pediatric patients and analyzed via untargeted metabolomic profiling by third party laboratory "Metabolon". Further analyses of these results were performed to help determine the relationship between changes in metabolites after antibiotic treatment and the development of antibiotic-associated neutropenia.

Files

Steps to reproduce

The R script used for metabolomics analysis is available at https://github.com/orgs/BCM-TCH-EpiCenter/repositories

Institutions

Baylor College of Medicine Department of Pediatrics

Categories

Pediatrics, Gut Microbiome, Untargeted Metabolomics

Funding

National Institutes of Health

R01 AI141716, R35HL155672, F31HL168921, T32GM136554, F31HL147514 A1, F31AI167538,

Cancer Prevention and Research Institute of Texas

RP210027

Licence