Electrospun biodegradable DegraPol® tubes with tissue inhibitor of matrixmetalloprotease-1 (TIMP-1) protein: Release kinetics, water contact angles and FTIR characterization

Published: 17 January 2025| Version 1 | DOI: 10.17632/3cm7sytr3r.1
Contributor:
Johanna Buschmann

Description

In order to have an implant material that modulates tendon healing with respect to fibrosis, tissue inhibitor of matrixmetalloprotease-1 (TIMP-1) protein has been incorporated into electrospun DegraPol® fiber meshes by emulsion electrospinning. We here present data on the characterization of such meshes, including release kinetics, static and dynamic water contact angles and FTIR spectra. In addition, the pure DegraPol® fiber mesh without TIMP-1 was characterized as control.

Files

Steps to reproduce

-

Institutions

Universitat Zurich, UniversitatsSpital Zurich

Categories

Controlled Release, Fourier Transform Infrared Spectroscopy, Biomedical Materials, Contact Angle, Drug Release

Funding

Swiss National Science Foundation

310030_197578

Licence