Mapping biological process relationships and disease perturbations within a pathway network - main results

Published: 9 Jul 2017 | Version 1 | DOI: 10.17632/3pbwkxjxg9.1
Contributor(s):

Description of this data

Set cover
The subset of pathways generated by the set cover, covering 100% of the genes and 99.95% of the genes are given in the tab delimited files are given by the set cover files.

Semantic distances
The 'all edges' file provides semantic distances in a text delimited file. One indicate the highest level of semantic similarity, lower numbers show reduced similarity.

Disease/ drug strings
list the terms used to filter for drug and disease terms

Cancer pathways
All cancer related pathways are supplied 'all cancer pathways.txt'
The sample of cancers used in figure 9 are in 'cancer pathway nodes.txt'. The GI and leukemia pathways in figure 10 are in 'cancer GI pathways.txt' and 'cancer leukemia pathways.txt'. These files are formated as node annotations for use with the multicolored nodes plugin.

Network files
'pathway network.cys' is a cytoscape file created in cytoscape 2.7
'edges bma wang.txt' contains the pathways used to generate the file
'functionally annotated in network.txt' contains the GO sample used in Figure 6. The file is formated as node annotations for use with the multicolored nodes plugin.

Experiment data files

Latest version

  • Version 1

    2017-07-09

    Published: 2017-07-09

    DOI: 10.17632/3pbwkxjxg9.1

    Cite this dataset

    Stoney, Ruth (2017), “Mapping biological process relationships and disease perturbations within a pathway network - main results”, Mendeley Data, v1 http://dx.doi.org/10.17632/3pbwkxjxg9.1

Statistics

Views: 616
Downloads: 92

Institutions

The University of Manchester

Categories

Systems Biology

Licence

CC BY 4.0 Learn more

The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.

What does this mean?
You can share, copy and modify this dataset so long as you give appropriate credit, provide a link to the CC BY license, and indicate if changes were made, but you may not do so in a way that suggests the rights holder has endorsed you or your use of the dataset. Note that further permission may be required for any content within the dataset that is identified as belonging to a third party.

Report