Discovery of dual GPBAR1 agonist and cysteinyl leukotriene receptor (CysLTR)1 antagonist for treating drug induced liver injury

Published: 5 January 2022| Version 1 | DOI: 10.17632/3xvs65zmhm.1
Contributors:
Michele Biagioli, Silvia Marchianò, Stefano Fiorucci

Description

In this research we have investigated the potential protective action of a dual GPBAR1 and CYSTLTR1 modulator in the development of hepatic inflammation and fibrosis in mice models of liver injury caused by acethaminophen (APAP) or CCL4

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Institutions

  • Universita degli Studi di Perugia

Categories

Transcriptomics

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