Lineage Plasticity and Mesenchymal-Stem Cell Enrichment in ACC: A Paired Transcriptomic Analysis of Primary Tumors and Derived Cell Lines for Modeling Recurrence
Published: 11 March 2026| Version 1 | DOI: 10.17632/4rtzb2cnc6.1
Contributors:
Tatiana Karpinets, Yoshitsugu Mitani, Michael Spiotto, Jie Li, Xingzhi Song, Raissa Relator, Haneen Al-Maghrabi, Irene Chen, Kai Deshpande, Daniele Heguedusch, Emilia Scalco Wachter, Jianhua Zhang, Renata Ferrarotto, Adel El-NaggarDescription
RNA-seq expression profiles of 12 cell lines and 9 paired primary tumor tissues of Adenoid Cystic Carcinoma (ACC). This dataset provides a comparative transcriptomic resource for studying the molecular characteristics of ACC, including the shift toward mesenchymal and stem-like phenotypes in in vitro models. Data files include a count matrix and sample metadata.
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Institutions
- The University of Texas MD Anderson Cancer CenterTexas, Houston
Categories
Salivary Gland Cancer, Cell Culture, Transcriptomics, Gene Expression Profiling