Novel therapeutic strategy for intractable keloids: Suppression of intracellular mechanotransduction and actin polymerization via Rho-kinase pathway inhibition

Published: 29 February 2024| Version 1 | DOI: 10.17632/4vkjnczg9m.1
Contributors:
Ji-Ung Park,
,
, Ki-Myo Kim, Mihyun Lee

Description

The STB-1400 mechanical stretching device (Strex Inc., Osaka, Japan) was used to expose cells to cyclic mechanical stretching (maximum 20% elongation, 10 cycles/min, 0.166 Hz) for 24 h, thereby mimicking the normal respiratory rate of healthy adults.

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Institutions

  • Seoul National University
  • Seoul National University Seoul Metropolitan Government Boramae Medical Center

Categories

Mechanotransduction

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