Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant
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Companion data directories for the 2024 PNAS article. Patrick Carmody,1† Francis J. Roushar,1† Austin Tedman,2 Wei Wang,3 Madeline Herwig,4 Minsoo Kim,4,5 Eli F. McDonald,4 Karen Noguera,1 Jennifer Wong-Roushar,1 Jon-Luc Poirier,1 Nathan B. Zelt,1 Ben T. Pockrass,1 Andrew G. McKee,1 Charles P. Kuntz,2 S. Vamsee Raju,3 Lars Plate,4,6 Wesley D. Penn,1* and Jonathan P. Schlebach2* 1 Department of Chemistry, Indiana University Bloomington, Bloomington, IN, USA 47401 2 The James Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, USA 47907 3 Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 35233 4Department of Chemistry, Vanderbilt University, Nashville, TN, USA 37240 5Program in Chemical and Physical Biology, Vanderbilt University, Nashville, TN, USA 37240 6Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA 37240
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National Institute of General Medical Sciences
R01GM138845
National Institute of General Medical Sciences
R35GM152086