Supplementary Material for"Color Doppler Ultrasound of Cosmetic Filler Complications: Associations with Filler Type and Injector Profession"

Description

This dataset contains supplementary and detailed study information from a retrospective study evaluating color Doppler ultrasound findings in 89 patients with cosmetic filler-related complications. The study investigated the ability of ultrasound to identify filler type and location and characterize associated complications, as well as associations between filler type, injector profession, complication onset, clinical manifestations, and sonographic findings. Color Doppler ultrasound was used to evaluate injected materials and associated tissue changes. The dataset includes information on hyaluronic acid (HA), polyacrylamide gel (PAAG), silicone, and polycaprolactone (PCL), as well as cases in which no filler could be identified. A substantial proportion of patients were unaware of the injected filler type, and discrepancies were observed between reported filler history and ultrasound findings, highlighting the potential value of imaging in evaluating filler-related complications. The dataset also demonstrates associations between injector profession and complication timing. Early complications, including vascular, infectious, and inflammatory manifestations, were more frequent among patients injected by non-physicians, whereas late complications, including granulomatous inflammation and persistent nodules, were more frequently observed among patients injected by dermatologists and non-dermatologist physicians. Sonographic findings included complex filler deposits with internal debris and surrounding inflammatory changes, granulomas, panniculitis, fluid collections, and vascular complications. Granulomas were particularly frequent in silicone and PCL cases, whereas vascular complications were observed exclusively among HA fillers in this study. Specific clinical manifestations were also associated with sonographic findings. Edema was associated with panniculitis, erythema/ulceration with fluid collections, and palpable nodules with several sonographic patterns, including granulomas, panniculitis, and complex filler deposits. These data support the potential role of color Doppler ultrasound as a non-invasive modality for identifying cosmetic filler materials and characterizing related complications. The dataset may be useful for researchers and clinicians studying adverse events associated with cosmetic fillers, ultrasound characteristics of injectable materials, and relationships between clinical manifestations and underlying tissue changes. However, findings should be interpreted in the context of the retrospective, single-center design and inclusion of patients presenting with complications; therefore, the dataset cannot be used to estimate overall complication rates for different filler types or injector professions. In accordance with the requirements of the Journal of the American Academy of Dermatology (JAAD), references have been removed from the manuscript.

Institutions

• Tehran University of Medical Sciences

  Tehran, Tehran
• Razi Hospital

  Tehran, Tehran

Categories

Licence