Oral iron plus ascorbic acid supplementation and martial status (Sideral; PI: P Perazzo)

Published: 25 October 2023| Version 2 | DOI: 10.17632/5p5xfj7gf2.2
Matteo Briguglio


Raw data of the clinical trial NCT04078880. We enrolled older adults scheduled for hip/knee surgery and we randomized them to a pre-operative supplementation program with iron and L-ascorbic acid or to the control group. Adjustments for confounding factors, such as iron absorption influencers, showed a relevant response limited to older patients (≥ 65 years old), whose uncharacterized Hb loss was averted upon treatment with iron formula. The dataset was used to write the article "Oral Supplementation with Sucrosomial Ferric Pyrophosphate Plus L-Ascorbic Acid to Ameliorate the Martial Status: A Randomized Controlled Trial", which was published by the Journal Nutrients in 2020.



IRCCS Istituto Ortopedico Galeazzi


Orthopedics, Functional Foods, Vitamin, Anemia, Iron, Dietary Supplement, Musculoskeletal Disorder, Nutraceuticals, Older Adult, Frailty