Preoperative primary tumor SUVmax on PET/CT correlates with Breslow thickness and is associated with survival in melanoma: A retrospective cohort study

Published: 4 September 2025| Version 1 | DOI: 10.17632/5wwx5w8rh4.1
Contributor:
WEI-TING LIU

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Supplementary Table I. Demographics and tumor characteristics of 31 patients with residual primary melanoma tumors that underwent PET/CT. Supplementary Figure 1. Subgroup analysis according to melanoma stage. (a) Patients with early-stage melanoma (Stage I-II) show a moderately positive correlation between SUVmax and Breslow thickness (r=0.585). (b) Patients with advanced-stage melanoma (Stage III-IV) show a strong correlation between SUVmax and Breslow thickness (r=0.618). Supplementary Figure 2. (a) Receiver operating characteristic (ROC) curve analysis identifying an SUVmax cutoff of 4.945 for predicting overall survival in melanoma patients. (b) Kaplan-Meier survival analysis demonstrating significantly worse survival rates in patients with SUVmax ≥ 4.945 compared to those with SUVmax < 4.945 (p=0.04, by Generalized Wilcoxon method).

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Positron Emission Tomography, Melanoma

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