Historical Grant Analysis and Timeline Appendix for DOI: 10.1016/j.nbd.2018.09.006
Description
"Houses official NIH grant file extracts, portal downloads, and recovered local drafts that cross-reference and verify separate biological experimental timelines. This folder includes '4016280_Egrant.pdf' for active award RF1AG057928, portal downloads ('EgrantAAZ.pdf') for proposal 1R01NS099161, and local abstract verifications ('1-16-IBS-008_Andjelkovic-Zochowska.pdf'). It also includes a recovered local backup draft ('ADADKAF.docx') validating the 2018 hardware storage drive failure and subsequent file recovery path described in the point-by-point defense."
Files
Steps to reproduce
Download and extract 'Grants_Part_1_Historical_Pilot_Data.zip' to access the early-stage, single-replicate (n=1) preliminary pilot experiment files generated years prior solely to establish proof-of-concept for funding applications (including 'CO_occludin_y_o_SAMPy_o_SAMP 30 sec.tif' and 'Co ZO1_cldn5_y_o_SAmp_1.tiff'). 2. Download and extract 'Grants_Part_2_Timeline_and_Verification_Files.zip' to audit official administrative timeline documentation, including the funded NIH Egrant file ('4016280_Egrant.pdf' for award RF1AG057928), proposal tracking files ('EgrantAAZ.pdf') for 1R01NS099161, and local abstract verifications ('1-16-IBS-008_Andjelkovic-Zochowska.pdf'). 3. Navigate to the primary manuscript raw data repository located at DOI: 10.17632/xs4hrrz26y.1 to access the full-length, uncropped primary manuscript instrument captures ('CLDN5 young old_bv.tif' and 'GAPDH young old_bv.tif'). 4. Cross-reference the lane configurations, sample volumes, and surrounding background architecture of the uncropped publication files in the first repository against the exploratory pilot data in Folder 1 of this repository. This comparison visually and chronologically verifies that the publication panels represent a separate, finalized 5-animal cohort (n=5) distinct from the grant pilots. 5. Review the recovered local backup text document ('ADADKAF.docx') in Folder 2 to trace the laboratory data recovery path following the 2018 hardware storage drive failure, confirming how these core publication files remained fully intact and unaltered.