Cross-Organ Hierarchy of HLA Molecular Mismatches in Donor-Specific Antibody Development in Solid Organ Transplantations

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This repository contains a comprehensive collection of R scripts, data files, results, and additional resources used in a research project examining the associations between eplet mismatches and the development of de novo donor-specific antibodies (DSA) in various transplant cohorts. This dataset is associated with the study ‘Cross-Organ Hierarchy of HLA Molecular Mismatches in Donor-Specific Antibody Development in Solid Organ Transplantations’ by M. Hirata, K. Tsukita, T. Shindo, et al. To easily calculate the Eplet Risk Score (ERS) using our web-based application, please visit: https://erscalculator.shinyapps.io/ers_application_deploy/.

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