L-BAIBA Synergizes with Sub-optimal Mechanical Loading to Promote New Bone Formation
Published: 14 April 2023| Version 1 | DOI: 10.17632/7ncthkxw26.1
Contributors:
Matthew Prideaux, Alberto Smargiassi, Gang Peng, Marco Brotto, Alex Robling, Lynda BonewaldDescription
To investigate potential mechanisms for the synergism of L-BAIBA and mechanical loading on bone formation, RNA Seq was performed on osteocyte-enriched cortical bone from mice treated with L-BAIBA and sub-optimal mechanical loading (8.25N) for either long-term (2 weeks L-BAIBA and loading) or short-term (5 days L-BAIBA and a single bout of mechanical loading). These supplementary data contain the differentially expressed genes and full GO pathway analysis used to create Figures 5-9 in the manuscript. A description for each supplemental file can be found in the 'Supplemental File Legends' document.
Files
Institutions
Indiana University Purdue University at Indianapolis
Categories
RNA Sequencing, Transcriptomics