The role of routine hematological indices in prognosis of acute ischemic stroke: a cross-sectional hospital-based study

Published: 20 March 2024| Version 4 | DOI: 10.17632/7rg9zvnfrp.4
Contributors:
Suman KC,
,
,
,

Description

A Descriptive cross-sectional study was conducted among patients admitted to the medicine ward with clinical and radiological evidence of ischemic stroke in Nepalgunj Medical College and Teaching Hospital (NGMCTH) after receiving ethical approval from the institutional review committee of the college. The confidentiality of all the participants was taken into account. Non-random sampling methods have been used. The study period spanned from April 18th, 2022, to June 17th, 2023, a period of 14 months. Data were collected using a pre-tested semi-structured self-administered questionnaire in printed form that includes detailed clinical history and physical examination. Collected data were entered in Microsoft Excel. Data were then analyzed statistically using Statistical Package for Social Sciences (SPSS Version 2022). The data were not normally distributed and the normality of data was tested using the Shapiro-Wilk test. The Spearman’s Correlation test was used to see the correlation between TLC, RDW, and ESR with mRS. The Chi-Square test was used to observe the association between mRS with TLC, RDW and ESR. A similar association was observed for the Glasgow coma scale (GCS) and Mortality. The evaluated data were presented in the form of tables and the association was considered to be significant if the p-value was less than 0.05. Out of 136 participants included in the study, 76 (55.9%) were male patients and 60 (44.1%) were female patients in total with the mean age of patients being 61.84 years. Most of the patients belonged to the age group of 56-60 years followed by the age group of 70-75 years. Hypertension was the most prevalent risk factor. Out of 136 patients, 47.05% had multiple risk factors, 44.85% had a single risk factor and 8.09% did not have any known risk factors.

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Data were collected using a pre-tested semi-structured self-administered questionnaire in printed form that includes detailed clinical history and physical examination. Collected data were entered in Microsoft Excel. Data were then analyzed statistically using Statistical Package for Social Sciences (SPSS Version 2022). The data were not normally distributed and the normality of data was tested using the Shapiro-Wilk test. The Spearman’s Correlation test was used to see the correlation between TLC, RDW, and ESR with mRS. The Chi-Square test was used to observe the association between mRS with TLC, RDW and ESR. A similar association was observed for the Glasgow coma scale (GCS) and Mortality. The evaluated data were presented in the form of tables and the association was considered to be significant if the p-value was less than 0.05.

Institutions

Nepalgunj Medical College

Categories

Internal Medicine, Clinical Neurology

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